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Rat Anti-LAMP1 Recombinant Antibody (1D4B) (CBMAB-0073-CN)

This product is a rat antibody that recognizes LAMP1 of mouse. The antibody 1D4B can be used for immunoassay techniques such as: ELISA, IF, IHC, IP, WB.
Host Species
Rat
Application
ELISA, IF, IHC, IP, WB
Immunogen
NIH/3T3 mouse embryo fibroblast tissue culture cell membranes
Antibody Isotype
IgG2a
Specificity
Mouse
Clone
1D4B
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.
Alternative Name
P2B; Perk; LGP-A; CD107a; Lamp-1; LGP-120
Entrez Gene ID
UniProt ID

This product has been referenced in:

Morin-Brureau, M., Milior, G., Royer, J., Chali, F., LeDuigou, C., Savary, E., ... & Navarro, V. (2018). Microglial phenotypes in the human epileptic temporal lobe. Brain, 141(12), 3343-3360.

Hughes, M. P., Smith, D. A., Morris, L., Fletcher, C., Colaco, A., Huebecker, M., ... & Waddington, S. N. (2018). AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann–Pick type C1 disease. Human molecular genetics, 27(17), 3079-3098.

Emperador-Melero, J., Huson, V., van Weering, J., Bollmann, C., von Mollard, G. F., Toonen, R. F., & Verhage, M. (2018). Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. Nature communications, 9(1), 3421.

Hou, H., Liu, W., Wu, S., Lu, Y., Peng, J., Zhu, Y., ... & Sun, Z. (2014). Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. PloS one, 9(10), e110585.

Qi, X., Man, S. M., Malireddi, R. S., Karki, R., Lupfer, C., Gurung, P., ... & Kanneganti, T. D. (2016). Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection. Journal of Experimental Medicine, 213(10), 2081-2097.

Cheadle, E. J., Lipowska-Bhalla, G., Dovedi, S. J., Fagnano, E., Klein, C., Honeychurch, J., & Illidge, T. M. (2017). A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells. Leukemia, 31(7), 1611.

Sun, C., Lan, P., Han, Q., Huang, M., Zhang, Z., Xu, G., ... & Sun, R. (2018). Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion. Nature communications, 9(1), 1241.

Yang, M., Chen, S., Du, J., He, J., Wang, Y., Li, Z., ... & Xu, P. (2016). NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nature communications, 7, 12730.

Hou, H., Liu, W., Wu, S., Lu, Y., Peng, J., Zhu, Y., ... & Sun, Z. (2014). Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. PloS one, 9(10), e110585.

Shifrin, N. T., Kissiov, D. U., Ardolino, M., Joncker, N. T., & Raulet, D. H. (2016). Differential role of hematopoietic and nonhematopoietic cell types in the regulation of nk cell tolerance and responsiveness. The Journal of Immunology, 197(10), 4127-4136.

Frenkel, D., Zhang, F., Guirnalda, P., Haynes, C., Bockstal, V., Radwanska, M., ... & Black, S. J. (2016). Trypanosoma brucei co-opts NK cells to kill splenic B2 B cells. PLoS pathogens, 12(7), e1005733.

Sudworth, A., Dai, K. Z., Vaage, J. T., & Kveberg, L. (2016). Degranulation response in cytotoxic rat lymphocytes measured with a novel CD107a antibody. Frontiers in immunology, 7, 572.

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For research use only. Not intended for any clinical use.
Cat CBMAB-0073-CN
Conjugates
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Second antibody and isotype control