Mouse Anti-PLAU Recombinant Antibody (SCU-PA) (CBMAB-P2028-YC)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
ChemotaxisManual Assertion Based On ExperimentTAS:ProtInc
FibrinolysisManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of fibrinolysis1 PublicationIC:ComplexPortal
Negative regulation of plasminogen activation1 PublicationIC:ComplexPortal
Plasminogen activationManual Assertion Based On ExperimentIDA:AgBase
Positive regulation of cell migrationManual Assertion Based On ExperimentIDA:MGI
ProteolysisManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell adhesionManual Assertion Based On ExperimentIDA:ComplexPortal
Regulation of cell adhesion mediated by integrinManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of cell population proliferationIEA:Ensembl
Regulation of fibrinolysis1 PublicationIC:ComplexPortal
Regulation of plasminogen activation1 PublicationIC:ComplexPortal
Regulation of signaling receptor activityManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of smooth muscle cell migrationManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of smooth muscle cell-matrix adhesionManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of wound healing1 PublicationIC:BHF-UCL
Response to hypoxiaIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Smooth muscle cell migrationIEA:Ensembl
Urokinase plasminogen activator signaling pathway1 PublicationIC:ComplexPortal
An autosomal dominant bleeding disorder due to a gain-of-function defect in fibrinolysis. Although affected individuals do not exhibit systemic fibrinolysis, they show delayed onset bleeding after challenge, such as surgery. The hallmark of the disorder is markedly increased PLAU levels within platelets, which causes intraplatelet plasmin generation and secondary degradation of alpha-granule proteins.
Produced as an inactive single-chain protein (pro-uPA or sc-uPA), is processed into the active disulfide-linked two-chain form of PLAU/uPA by a proteolytic event mediated, at least, by TMPRSS4.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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