Mouse Anti-TNFSF13B Recombinant Antibody (CBT4314) (V2LY-0625-LY683)
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Basic Information
| Application | Note |
| WB | 1:500-1:2,000 |
| ICC | 1:100-1:500 |
| FC | 1:200-1:400 |
| ELISA | 1:10,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Isoform 2 seems to inhibit isoform 1 secretion and bioactivity.
Isoform 3
Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly regulate the differential expression of a large number of genes involved in the innate immune response and the regulation of apoptosis.
Biological Process B cell differentiation Source:Ensembl
Biological Process B cell homeostasis Source:Ensembl
Biological Process B cell proliferation Source:Ensembl
Biological Process germinal center formation Source:Ensembl
Biological Process positive regulation of B cell proliferation Source:AgBase1 Publication
Biological Process positive regulation of germinal center formation Source:Ensembl
Biological Process positive regulation of T cell proliferation Source:Ensembl
Biological Process signal transduction Source:ProtInc1 Publication
Biological Process T cell costimulation Source:Ensembl
Biological Process T cell proliferation Source:Ensembl
Biological Process tumor necrosis factor-mediated signaling pathway Source:Ensembl
Tumor necrosis factor ligand superfamily member 13b, soluble form
Secreted
Helical: 47-67
Extracellular: 68-285
Isoform 2 is not efficiently shed from the membrane unlike isoform 1.
N-glycosylated.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
TNFSF13B Matched Antibody Pair (1239) (CAT#: APMAB-1239LY)
TNFSF13B Matched Antibody Pair (1241) (CAT#: APMAB-1241LY)
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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