Mouse Anti-TWIST2 Recombinant Antibody (CBYJT-5415) (CBMAB-T5021-YJ)

Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Biological Process developmental process Source:GO_Central1 Publication
Biological Process negative regulation of apoptotic process Source:Ensembl
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB
Biological Process negative regulation of osteoblast differentiation Source:UniProtKB1 Publication
Biological Process positive regulation of cell migration Source:BHF-UCL1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process response to insulin Source:Ensembl
Biological Process response to organic cyclic compound Source:Ensembl
Cytoplasm
Mainly nuclear during embryonic development. Cytoplasmic in adult tissues.
A form of focal facial dermal dysplasia, a group of developmental defects characterized by bitemporal or preauricular skin lesions resembling aplasia cutis congenita. FFDD3 is characterized by distinctive bitemporal scar-like depressions resembling forceps marks, and additional facial features, including a coarse and leonine appearance, absent eyelashes on both lids or multiple rows on the upper lids, absent Meibomian glands, slanted eyebrows, chin clefting, and hypo- or hyperpigmentation of the skin. Histologically, the bitemporal lesion is an ectodermal dysplasia with near absence of subcutaneous fat, suggesting insufficient migration of neural crest cells into the frontonasal process and the first branchial arch.
Ablepharon-macrostomia syndrome (AMS):
A congenital ectodermal dysplasia characterized by absent eyelids, macrostomia, microtia, redundant skin, sparse hair, dysmorphic nose and ears, variable abnormalities of the nipples, genitalia, fingers, and hands, largely normal intellectual and motor development, and poor growth.
Barber-Say syndrome (BBRSAY):
A rare ectodermal dysplasia characterized by ectropion, macrostomia, ear abnormalities, broad nasal bridge, bulbous nose, redundant skin, hypertrichosis, dental abnormalities, and variable other features.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
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Mouse Anti-TWIST2 Recombinant Antibody (CBYJT-5420) (CAT#: CBMAB-T5026-YJ)
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Mouse Anti-TWIST2 Recombinant Antibody (1E2) (CAT#: CBMAB-A9665-LY)
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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