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EXOSC5 Matched Antibody Pair (391) (APMAB-391LY)

This antibody pair set can be used for detecting and quantifying protein level of human EXOSC5.
See all EXOSC5 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-EXOSC5 monoclonal, IgG2a antibody, 100 ug
Detection Antibody
Anti-EXOSC5 Biotinylated mouse monoclonal, IgG2a antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
EXOSC5 (Exosome Component 5) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and exoribonuclease activity.
Alternative Names
Exosome Component 5; Chronic Myelogenous Leukemia Tumor Antigen 28; Ribosomal RNA-Processing Protein 46; Exosome Component Rrp46; RRP46; P12B; Exosome Complex Exonuclease RRP46;
Entrez Gene ID
56915
UniProt ID
Q9NQT4

Zhang, Y., Yang, X., Hu, Y., & Huang, X. (2022). Integrated Bioinformatic Investigation of EXOSCs in Hepatocellular Carcinoma Followed by the Preliminary Validation of EXOSC5 in Cell Proliferation. International Journal of Molecular Sciences, 23(20), 12161.

Chen, X., Huang, Y., Liu, J., Lin, W., Chen, C., Chen, Y., ... & Teng, L. (2022). EXOSC5 promotes proliferation of gastric cancer through regulating AKT/STAT3 signaling pathways. Journal of Cancer, 13(5), 1456.

Calame, D. G., Herman, I., Fatih, J. M., Du, H., Akay, G., Jhangiani, S. N., ... & Miyake, C. Y. (2021). Risk of sudden cardiac death in EXOSC5‐related disease. American Journal of Medical Genetics Part A, 185(8), 2532-2540.

Pan, H., Pan, J., Song, S., Ji, L., Lv, H., & Yang, Z. (2021). Corrigendum: EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways. Frontiers in Oncology, 11, 670041.

Slavotinek, A., Misceo, D., Htun, S., Mathisen, L., Frengen, E., Foreman, M., ... & Corbett, A. H. (2020). Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness. Human Molecular Genetics, 29(13), 2218-2239.

Schneidman-Duhovny, J. E. V., Duncan, J. L., Haaxma, C. A., Kamsteeg, E. J., Xia, V., Beleford, D., ... & Corbett, A. H. (2020). Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness Anne Slavotinek1,†,*, Doriana Misceo2,†, Stephanie Htun1, Linda Mathisen2, Eirik Frengen2, Michelle Foreman3, Jennifer E. Hurtig3, Liz Enyenihi4, Maria C. Sterrett4, Sara W. Leung4, Dina. Human Molecular Genetics, 29(13), 2218-2239.

Pan, H., Pan, J., Song, S., Ji, L., Lv, H., & Yang, Z. (2019). EXOSC5 as a novel prognostic marker promotes proliferation of colorectal cancer via activating the ERK and AKT pathways. Frontiers in oncology, 9, 643.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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