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HOXB9 Matched Antibody Pair (567) (APMAB-567LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-HOXB9 polyclonal antibody, 100 ug
Detection Antibody
Anti-HOXB9 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]
Alternative Names
Homeobox B9; Homeobox Protein Hox-2.5; Homeobox Protein Hox-2E; Homeo Box B9; HOX2E; Homeobox Protein Hox-B9; Homeo Box 2E; HOX-2.5; HOX2;
Entrez Gene ID
UniProt ID
More Infomation

Wang, T., Guo, H., Li, Q., Wu, W., Yu, M., Zhang, L., ... & Zhan, J. (2022). The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations. Cell Reports, 40(8).

Yao, Y., Liu, C., Wang, B., Guan, X., Fang, L., Zhan, F., ... & Zhang, Y. (2022). HOXB9 blocks cell cycle progression to inhibit pancreatic cancer cell proliferation through the DNMT1/RBL2/c-Myc axis. Cancer Letters, 533, 215595.

Martinou, E., Falgari, G., Bagwan, I., & Angelidi, A. M. (2021). A systematic review on HOX genes as potential biomarkers in colorectal cancer: an emerging role of HOXB9. International journal of molecular sciences, 22(24), 13429.

Zheng, H., Li, C., Li, Z., Zhu, K., Bao, H., Xiong, J., & Liang, P. (2021). HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier. Aging (Albany NY), 13(4), 4999.

Zhang, L., Wu, Q., He, C., Liang, D., Yi, Q., Shi, J., ... & Chang, Q. (2019). HOXB9 inhibits proliferation in gastric carcinoma cells via suppression of phosphorylated-Akt and NF-κB-dependent Snail expression. Digestive and Liver Disease, 51(1), 157-165.

Kato, F., Wada, N., Hayashida, T., Fukuda, K., Nakamura, R., Takahashi, T., ... & Kitagawa, Y. (2019). Experimental and clinicopathological analysis of HOXB9 in gastric cancer. Oncology letters, 17(3), 3097-3102.

Xiong, H., Xiao, H., Luo, C., Chen, L., Liu, X., Hu, Z., ... & Wang, K. (2019). GRP78 activates the Wnt/HOXB9 pathway to promote invasion and metastasis of hepatocellular carcinoma by chaperoning LRP6. Experimental Cell Research, 383(1), 111493.

Song, J., Wang, T., Xu, W., Wang, P., Wan, J., Wang, Y., ... & Zhang, H. (2018). HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression. Cancer Letters, 426, 63-72.

Wan, J., Liu, H., Feng, Q., Liu, J., & Ming, L. (2018). HOXB9 promotes endometrial cancer progression by targeting E2F3. Cell death & disease, 9(5), 509.

Lin, J., Zhang, D., Fan, Y., Chao, Y., Chang, J., Li, N., ... & Han, C. (2018). Regulation of cancer stem cell self-renewal by HOXB9 antagonizes endoplasmic reticulum stress-induced melanoma cell apoptosis via the miR-765–FOXA2 axis. Journal of Investigative Dermatology, 138(7), 1609-1619.

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For research use only. Not intended for any clinical use.

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