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ACSS2

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Full Name
acyl-CoA synthetase short-chain family member 2
Function
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity (By similarity).
Biological Process
Acetate biosynthetic process
Acetyl-CoA biosynthetic process from acetate
Ethanol oxidation
Lipid biosynthetic process
Propionate biosynthetic process
Cellular Location
Cytosol
PTM
Reversibly acetylated at Lys-661 (By similarity). The acetyl-CoA synthase activity is inhibited by acetylation and activated by deacetylation mediated by the deacetylases SIRT1 and SIRT3 (By similarity).
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Anti-ACSS2 antibodies

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Rabbit Anti-ACSS2 Recombinant Antibody (V2-179458) (CBMAB-A0772-YC)

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Target: ACSS2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: V2-179458
Application*: WB, IP
Datasheet SDS

Mouse Anti-ACSS2 Recombinant Antibody (V2-179457) (CBMAB-A0771-YC)

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Target: ACSS2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-179457
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ACSS2 Recombinant Antibody (V2-179454) (CBMAB-A0767-YC)

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Target: ACSS2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-179454
Application*: P, WB
Datasheet SDS

Mouse Anti-ACSS2 Recombinant Antibody (V2-179453) (CBMAB-A0765-YC)

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Target: ACSS2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-179453
Application*: F, WB
Datasheet SDS

Mouse Anti-ACSS2 Recombinant Antibody (V2-179450) (CBMAB-A0762-YC)

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Target: ACSS2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-179450
Application*: WB
Datasheet SDS

Mouse Anti-ACSS2 Recombinant Antibody (V2-179449) (CBMAB-A0760-YC)

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Target: ACSS2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-179449
Application*: E, IF, WB
Datasheet SDS

Rabbit Anti-ACSS2 Recombinant Antibody (V2-179448) (CBMAB-A0759-YC)

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Target: ACSS2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey, Mouse, Rat
Clone: V2-179448
Application*: IP, WB
Datasheet SDS

Mouse Anti-ACSS2 Recombinant Antibody (V2-6070) (CBMAB-0015CQ)

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Target: ACSS2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-6070
Application*: IH, WB
Datasheet SDS

Mouse Anti-ACSS2 Recombinant Antibody (V2-6069) (CBMAB-0014CQ)

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Target: ACSS2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-6069
Application*: P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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