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CA3

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.

Full Name

CA3

Function

Reversible hydration of carbon dioxide.

Biological Process

Bicarbonate transport Source: Reactome
One-carbon metabolic process Source: GO_Central
Response to bacterium Source: Ensembl
Response to ethanol Source: Ensembl
Response to oxidative stress Source: Ensembl

Cellular Location

Cytoplasm

PTM

S-glutathionylated in hepatocytes under oxidative stress.

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Anti-CA3 antibodies

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Mouse Anti-CA3 Recombinant Antibody (CBXC-1769) (CBMAB-C3292-CQ)

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Target: CA3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-1769

Application*: E

Mouse Anti-CA3 Recombinant Antibody (4A12-1A3) (CBMAB-C6561-LY)

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Target: CA3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 4A12-1A3

Application*: E, IH, WB

Rabbit Anti-CA3 Recombinant Antibody (006) (CBMAB-C1530-LY)

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Target: CA3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 006

Application*: WB, IP

Rabbit Anti-CA3 Recombinant Antibody (002) (CBMAB-C1479-LY)

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Target: CA3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 002

Application*: P

CA3 Matched Antibody Pair (164) (APMAB-164LY)

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Target: CA3

Specificity: Human

Mouse Anti-CA3 Recombinant Antibody (CBXC-2891) (CBMAB-C3293-CQ)

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Target: CA3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse, Rat, Pig

Clone: CBXC-2891

Application*: WB, IF, P, IP

Mouse Anti-CA3 Recombinant Antibody (CBYY-C0254) (CBMAB-C0740-YY)

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Target: CA3

Host: Mouse

Antibody Isotype: IgG3, ĸ

Specificity: Human, Mouse, Rat

Clone: CBYY-C0254

Application*: E, WB, IF, P, IP

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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