Mouse Anti-CA3 Recombinant Antibody (CBXC-2891) (CBMAB-C3293-CQ)

Name: Mouse Anti-CA3 Recombinant Antibody (CBXC-2891)
SKU: CBMAB-C3293-CQ
Rating: 5 (1 reviews)

See all CA3 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXC-2891

Application

WB, IF, P, IP

Immunogen

Recombinant protein

Host Species

Mouse

Specificity

Human, Mouse, Rat, Pig

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	0.5-2 µg/ml
IHC	5-20 µg/ml
IF(ICC)	5-20 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 50% glycerol

Preservative

0.05% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

CA3

Introduction

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.

Entrez Gene ID

761

UniProt ID

P07451

Alternative Names

CAIII; Car3

Function

Reversible hydration of carbon dioxide.

Biological Process

Bicarbonate transport Source: Reactome
One-carbon metabolic process Source: GO_Central
Response to bacterium Source: Ensembl
Response to ethanol Source: Ensembl
Response to oxidative stress Source: Ensembl

Cellular Location

Cytoplasm

PTM

S-glutathionylated in hepatocytes under oxidative stress.

Liu, D., Wong, C. C., Zhou, Y., Li, C., Chen, H., Ji, F., ... & Yu, J. (2021). Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target. Gastroenterology, 160(7), 2467-2482.

NG, B., & Budak, H. (2021). Tip60 Might Be a Candidate For The Acetylation of Hepatic Carbonic Anhydrase I and III in Mice.

BALTACI, N. G., KOCPINAR, E. F., & Budak, H. (2021). Tip60 Might Be a Candidate For The Acetylation of Hepatic Carbonic Anhydrase I and III in Mice.

Aspatwar, A., Hammaren, M., Parikka, M., Parkkila, S., Carta, F., Bozdag, M., ... & Supuran, C. T. (2020). In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono-and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos. Journal of enzyme inhibition and medicinal chemistry, 35(1), 65-71.

Barhwal, K. K., Biswal, S., Nag, T. C., Chaurasia, O. P., & Hota, S. K. (2020). Class switching of carbonic anhydrase isoforms mediates remyelination in CA3 hippocampal neurons during chronic hypoxia. Free Radical Biology and Medicine, 161, 102-114.

Roy, P., Ireland, M., Roy, S., Craft, J., & Bartholomew, C. (2018). Carbonic Anhydrase III S-Glutathionylation Is Necessary for Anti-Oxidant Activity. Yangtze Medicine, 2(04), 244.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-CA3 Recombinant Antibody (CBXC-2891)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

CA3 Matched Antibody Pair (164) (CAT#: APMAB-164LY)

Related Products

Mouse Anti-CA3 Recombinant Antibody (CBXC-1769) (CAT#: CBMAB-C3292-CQ)

Mouse Anti-CA3 Recombinant Antibody (4A12-1A3) (CAT#: CBMAB-C6561-LY)

Mouse Anti-CA3 Recombinant Antibody (CBYY-C0254) (CAT#: CBMAB-C0740-YY)

CA3 Matched Antibody Pair (164) (CAT#: APMAB-164LY)

Rabbit Anti-CA3 Recombinant Antibody (006) (CAT#: CBMAB-C1530-LY)

Rabbit Anti-CA3 Recombinant Antibody (002) (CAT#: CBMAB-C1479-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry