CAPZA2

CAPZA2 (Capping Actin Protein Of Muscle Z-Line Alpha Subunit 2) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is CAPZA1.

Full Name

Capping Actin Protein Of Muscle Z-Line Alpha Subunit 2

Function

F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

Biological Process

Actin cytoskeleton organization Source: GO_Central
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Barbed-end actin filament capping Source: GO_Central
Blood coagulation Source: Reactome
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Innate immune response Source: Reactome
Protein-containing complex assembly Source: ProtInc

Cellular Location

Actin cytoskeleton; Cortical cytoskeleton; F-actin capping protein complex; Cytosol; Extracellular exosome; Extracellular region; Brush border; Membrane

Anti-CAPZA2 antibodies

Mouse Anti-CAPZA2 Recombinant Antibody (CBYY-C0942) (CBMAB-C2379-YY)

Datasheet

SDS

Target: CAPZA2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C0942

Application*: WB, E

Mouse Anti-CAPZA2 Recombinant Antibody (EG476) (CBMAB-EN540-LY)

Datasheet

SDS

Target: CAPZA2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: EG476

Application*: ELISA, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)