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CASP3

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

Anti-CASP3 antibodies

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Cat Product Name Target Host Antibody Isotype Cross Reactivity Clone Application*
CBMAB-C8977-LY Mouse Anti-CASP3 Recombinant Antibody (84803) CASP3 Mouse IgG2b Human 84803 WB
CBMAB-C8168-LY Mouse Anti-CASP3 Recombinant Antibody (6D218) CASP3 Mouse IgG1 Human 6D218 WB
CBMAB-C7262-LY Rabbit Anti-CASP3 Recombinant Antibody (5A1E) CASP3 Rabbit IgG Human, Mouse, Rat, Monkey, Dog 5A1E WB, IP, P, C, IF, F
CBMAB-C0267-YY Mouse Anti-CASP3 Recombinant Antibody (3CSP01 (7.1.44)) CASP3 Mouse IgG2a Human 3CSP01 (7.1.44) F, P, IP, WB
CBMAB-C0899-FY Mouse Anti-CASP3 Recombinant Antibody (CBFYC-0844) CASP3 Mouse IgG1 Human CBFYC-0844 WB
CBMAB-C0897-FY Mouse Anti-CASP3 (AA 1-219) Recombinant Antibody (CBFYC-0842) CASP3 Mouse IgG2a Human CBFYC-0842 WB, IP
CBMAB-C0896-FY Mouse Anti-CASP3 Recombinant Antibody (CBFYC-0841) CASP3 Mouse IgG2b Human CBFYC-0841 E, IH, WB
CBMAB-C0895-FY Mouse Anti-CASP3 Recombinant Antibody (CBFYC-0840) CASP3 Mouse IgG1 Human CBFYC-0840 WB
CBMAB-C0893-FY Mouse Anti-CASP3 Recombinant Antibody (CBFYC-0838) CASP3 Mouse IgG1 Human CBFYC-0838 IH, WB
CBMAB-C0892-FY Rat Anti-CASP3 Recombinant Antibody (CBFYC-0837) CASP3 Rat IgG2a Human CBFYC-0837 WB
CBMAB-C7094-LY Mouse Anti-CASP3 Recombinant Antibody (4i29) CASP3 Mouse IgG2a Human 4i29 E, DB
CBMAB-C7056-LY Mouse Anti-CASP3 Recombinant Antibody (4H41) CASP3 Mouse IgG1, κ Human 4H41 E, WB
CBMAB-C7050-LY Rabbit Anti-CASP3 Recombinant Antibody (4H334) CASP3 Rabbit IgG Mouse, Human, Monkey 4H334 WB, IP, IC
CBMAB-C9201-LY Rabbit Anti-CASP3 Recombinant Antibody (8G10) CASP3 Rabbit IgG Human, Mouse, Rat, Monkey 8G10 WB, IP
CBMAB-C6682-LY Mouse Anti-CASP3 Recombinant Antibody (4B8) CASP3 Mouse IgG Human, Mouse, Rat 4B8 P
CBMAB-C5844-LY Mouse Anti-CASP3 Recombinant Antibody (3CSP01 7.1.44) CASP3 Mouse IgG2a Human 3CSP01 7.1.44 F, P, IP, WB
CBMAB-C1268-LY Mouse Anti-CASP3 Recombinant Antibody (4-1-18) CASP3 Mouse IgG2a Human 4-1-18 WB
CBMAB-C1122-LY Mouse Anti-CASP3 Recombinant Antibody (3F49) CASP3 Mouse IgG2a Human 3F49 IH, IP, WB
CBMAB-C8615-LY Rat Anti-CASP3 Recombinant Antibody (7D12) CASP3 Rat IgG2b Human 7D12 WB
CBMAB-C8503-LY Mouse Anti-CASP3 Recombinant Antibody (74T2) CASP3 Mouse IgG1 Horse, Human, Mouse, Primate, Rat 74T2 F, IC, IF, P, IP, WB
CBMAB-C7705-LY Mouse Anti-CASP3 Recombinant Antibody (5H10) CASP3 Mouse IgG Human, Mouse, Rat 5H10 P
CBMAB-C6783-LY Mouse Anti-CASP3 Recombinant Antibody (4D3) CASP3 Mouse IgG2a, κ Human 4D3 E
CBMAB-C6171-LY Mouse Anti-CASP3 Recombinant Antibody (3G64) CASP3 Mouse IgG2a Human 3G64 C, WB
CBMAB-C6125-LY Mouse Anti-CASP3 Recombinant Antibody (3G2) CASP3 Mouse IgG1 Human 3G2 WB
CBMAB-C6050-LY Mouse Anti-CASP3 Recombinant Antibody (3F47) CASP3 Mouse IgG2a Human 3F47 IH, IP, WB
CBMAB-C2744-LY Mouse Anti-CASP3 Recombinant Antibody (13A242) CASP3 Mouse IgG1 Human, Mouse, Rat 13A242 WB
CBMAB-C1097-LY Mouse Anti-CASP3 Recombinant Antibody (3D4D7) CASP3 Mouse IgG Human 3D4D7 WB, F, E, IH, IC, MC
CBMAB-A4277-YC Mouse Anti-CASP3 Recombinant Antibody (1C12) CASP3 Mouse IgG1 Human, Mouse 1C12 WB, P
CBMAB-C5791-LY Mouse Anti-CASP3 Recombinant Antibody (3C119) CASP3 Mouse IgG2a, κ Human 3C119 E, WB
CBMAB-C4096-LY Mouse Anti-CASP3 Recombinant Antibody (1F9) CASP3 Mouse IgG1 Human 1F9 WB, P
CBMAB-C4041-LY Rat Anti-CASP3 Recombinant Antibody (1F3) CASP3 Rat IgG2a Human 1F3 WB
CBMAB-C3975-LY Mouse Anti-CASP3 Recombinant Antibody (1E7F9) CASP3 Mouse IgG2b Human 1E7F9 E, C, WB
CBMAB-C1652-LY Mouse Anti-CASP3 Recombinant Antibody (02) CASP3 Mouse IgG1 Human 02 F
CBMAB-C1321-LY Mouse Anti-CASP3 Recombinant Antibody (46/Caspase-3) CASP3 Mouse IgG1 Mouse 46/Caspase-3 WB, IF, IP
CBMAB-C0450-LY Mouse Anti-CASP3 Recombinant Antibody (19/Caspase-3/CPP32) CASP3 Mouse IgG2a Human 19/Caspase-3/CPP32 WB, IP
CBMAB-C9248-LY Mouse Anti-CASP3 Recombinant Antibody (8J1351) CASP3 Mouse IgG Human 8J1351 WB
CBMAB-C1334-CN Rabbit Anti-CASP3 Recombinant Antibody (9j114) CASP3 Rabbit IgG Human, Monkey, Mouse, Rat 9j114 IP, WB
CBMAB-C5013-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-0075) CASP3 Mouse IgG Human, Rat, Mouse CBXC-0075 IH
CBMAB-C5012-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-0077) CASP3 Mouse IgG1 Human, Mouse, Rat CBXC-0077 WB
CBMAB-C5011-CQ Rabbit Anti-CASP3 Recombinant Antibody (CBXC-1053) CASP3 Rabbit IgG Human, Mouse CBXC-1053 WB, IC
CBMAB-C5010-CQ Rabbit Anti-CASP3 Recombinant Antibody (CBXC-0950) CASP3 Rabbit IgG Human CBXC-0950 IC
CBMAB-C5009-CQ Rat Anti-CASP3 Recombinant Antibody (CBXC-1994) CASP3 Rat IgG2a Human CBXC-1994 WB
CBMAB-C5008-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-2008) CASP3 Mouse IgG1 Human CBXC-2008 IH, WB
CBMAB-C5007-CQ Mouse Anti-CASP3 Recombinant Antibody (AMI-3-1-11) CASP3 Mouse IgG2a Human AMI-3-1-11 IP
CBMAB-C5006-CQ Rabbit Anti-CASP3 Recombinant Antibody (CBXC-1697) CASP3 Rabbit IgG Human, Rat CBXC-1697 IC, IH, IP, WB
CBMAB-C5004-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-0076) CASP3 Mouse IgG Human, Mouse CBXC-0076 P, WB
CBMAB-C5003-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-2276) CASP3 Mouse IgG1 Human CBXC-2276 P, WB
CBMAB-C3200-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-0078) CASP3 Mouse IgG2a Human CBXC-0078 IH, IP, WB
CBMAB-C0187-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-2841) CASP3 Mouse IgG Human CBXC-2841 WB, F, E, IH
CBMAB-C0186-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-2840) CASP3 Mouse IgG Human, Mouse, Rat CBXC-2840 WB, F, E, IH
CBMAB-C0167-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-2792) CASP3 Mouse IgG Human CBXC-2792 WB, IH, P
CBMAB-C0166-CQ Mouse Anti-CASP3 Recombinant Antibody (CBXC-2791) CASP3 Mouse IgG1, κ Human, Mouse, Rat, Pig, Chinese Hamster, Mammal CBXC-2791 WB, F, IF, P, C
CBMAB-P0137-YC Rabbit Anti-CASP3 Recombinant Antibody (E61) CASP3 Rabbit IgG Human E61 P
CBMAB-C2412-YY Rabbit Anti-CASP3 Recombinant Antibody (CBYY-C0975) CASP3 Rabbit IgG Human, Mouse, Rat, Monkey CBYY-C0975 WB, IP
CBMAB-C2411-YY Mouse Anti-CASP3 Recombinant Antibody (CBYY-C0974) CASP3 Mouse IgG1 Equine, Human, Mouse, Primate, Rat CBYY-C0974 F, IC, IF, P, IP, WB
CBMAB-C2410-YY Mouse Anti-CASP3 Recombinant Antibody (CBYY-C0973) CASP3 Mouse IgG Human, Mouse, Rat CBYY-C0973 P
CBMAB-C2409-YY Mouse Anti-CASP3 Recombinant Antibody (CBYY-C0972) CASP3 Mouse IgG Human, Mouse, Rat CBYY-C0972 P
CBMAB-C2408-YY Mouse Anti-CASP3 Recombinant Antibody (CBYY-C0971) CASP3 Mouse IgG2a Human CBYY-C0971 E, D
CBMAB-C2407-YY Rabbit Anti-CASP3 Recombinant Antibody (CBYY-C0970) CASP3 Rabbit IgG Mouse, Human, Monkey CBYY-C0970 WB, IP, IC
CBMAB-C2406-YY Mouse Anti-CASP3 Recombinant Antibody (CBYY-C0969) CASP3 Mouse IgG2a Human CBYY-C0969 IH, IP, WB
CBMAB-0955-YC Mouse Anti-CASP3 Monoclnal Antibody (1262CT521.280.101) CASP3 Mouse IgG1 Human 1262CT521.280.101 E, WB
CBMAB-1313-CN Rabbit Anti-CASP3 Recombinant Antibody (E83-77) CASP3 Rabbit IgG Human E83-77 IF, C, P, WB
CBMAB-0160CQ Mouse Anti-CASP3 Recombinant Antibody (BA0429) CASP3 Mouse IgG Human BA0429 WB, IF, IH
CBMAB-0159CQ Mouse Anti-CASP3 Recombinant Antibody (3D4D10) CASP3 Mouse IgG Human, Mouse, Rat 3D4D10 WB, E, F, IH, MC, IC
CBMAB-0158CQ Rabbit Anti-CASP3 Recombinant Antibody (2A3) CASP3 Rabbit IgG Human, Mouse 2A3 WB, IC
CBMAB-0157CQ Rabbit Anti-CASP3 Recombinant Antibody (1112I) CASP3 Rabbit IgG Human 1112I IC
CBMAB-0156CQ Mouse Anti-CASP3 Recombinant Antibody (31A1067) CASP3 Mouse IgG1, κ Human, Mouse, Rat, Pig, Chicken, Hamster 31A1067 WB, EM, F, IF, IH, C, P, MC
CBMAB-0155CQ Mouse Anti-CASP3 Recombinant Antibody (CPP32 4-1-18) CASP3 Mouse IgG2a, κ Human, Mouse, Rat CPP32 4-1-18 WB, IH, P
CBMAB-0154CQ Mouse Anti-CASP3 Recombinant Antibody (2A8) CASP3 Mouse IgG2b Human 2A8 WB
CBMAB-0153CQ Mouse Anti-CASP3 Recombinant Antibody (31A893) CASP3 Mouse IgG Human 31A893 WB, IF, IH, P
CBMAB-Ab043-LY Recombinant Rabbit Anti-CASP3Antibody (CBAb043) CASP3 Rabbit IgG Human, Rat CBAb043 WB, IH, IF, IP
CBMAB-C0268-YY Mouse Anti-CASP3 Recombinant Antibody (3CSP03) CASP3 Mouse IgG2a Human 3CSP03 IH, C, P, IP, WB, F, IC, IF
CBMAB-Z0233-LY Mouse Anti-CASP3 Recombinant Antibody (1H11-G3-F8) CASP3 Mouse IgG1 Human, Mouse, Rat 1H11-G3-F8 WB, IH, IC, F
CBMAB-Ab006-LY Recombinant Rabbit Anti-CASP3Antibody (CBAb006) CASP3 Rabbit IgG Human CBAb006 WB, IH, IF
CBMAB-CP0108-LY Rabbit Anti-CASP3 Recombinant Antibody (D3R6Y) CASP3 Rabbit IgG Human D3R6Y P
CBMAB-C1337-CN Mouse Anti-CASP3 Recombinant Antibody (CBCNC-144) CASP3 Mouse Rat CBCNC-144 WB, ICC, P, IH-F, E
CBMAB-C1336-CN Mouse Anti-CASP3 Recombinant Antibody (C33) CASP3 Mouse IgG1 Human, Mouse, Rat C33 WB
CBMAB-C1335-CN Mouse Anti-CASP3 Recombinant Antibody (AM1-4) CASP3 Mouse IgG Human AM1-4 WB
CBMAB-C9731-LY Mouse Anti-CASP3 Recombinant Antibody (SB71b) CASP3 Mouse IgG2a Human SB71b WB
CBMAB-C2005-YY Mouse Anti-CASP3 Recombinant Antibody (CBYY-C0680) CASP3 Mouse IgG2b Human CBYY-C0680 WB
CBMAB-C0690-YY Mouse Anti-CASP3 Recombinant Antibody (CBYY-C0237) CASP3 Mouse IgG1 Mouse CBYY-C0237 WB, IF, IP
PEP-073348CQ Dog CASP3 Peptide (KVATEFESF) CASP3
PEP-121011CQ Human CASP3 Peptide (NGPVDLKKI) CASP3
PEP-007859CQ Human CASP3 Peptide (GTNGPVDLKK) CASP3
PEP-007858CQ Human CASP3 Peptide (SLDNSYKMDY) CASP3
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)