CDC42EP2
CDC42EP2 (CDC42 Effector Protein 2) is a Protein Coding gene. Among its related pathways are Actin Nucleation by ARP-WASP Complex and G-protein signaling RAC1 in cellular process. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and opioid peptide activity. An important paralog of this gene is CDC42EP3.
Full Name
CDC42 Effector Protein 2
Function
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Biological Process
Actin cytoskeleton organization Source: UniProtKB
Actin filament organization Source: UniProtKB
Cellular response to interferon-gamma Source: Ensembl
Positive regulation of actin filament polymerization Source: UniProtKB
Positive regulation of protein-containing complex assembly Source: UniProtKB
Positive regulation of pseudopodium assembly Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Rho protein signal transduction Source: GO_Central
Actin filament organization Source: UniProtKB
Cellular response to interferon-gamma Source: Ensembl
Positive regulation of actin filament polymerization Source: UniProtKB
Positive regulation of protein-containing complex assembly Source: UniProtKB
Positive regulation of pseudopodium assembly Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Rho protein signal transduction Source: GO_Central
Cellular Location
Cytoskeleton; Endomembrane system
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Anti-CDC42EP2 antibodies
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Target: CDC42EP2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: EG403
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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