Sign in or Register

DOK1

DOK1 is part of a signal transduction pathway downstream of receptor tyrosine kinases. The protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes.
Full Name
Docking Protein 1
Function
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Biological Process
Cell surface receptor signaling pathway Source: ProtInc
Macrophage colony-stimulating factor signaling pathway Source: Ensembl
Ras protein signal transduction Source: Ensembl
Signal transduction Source: ProtInc
Transmembrane receptor protein tyrosine kinase signaling pathway Source: ProtInc
Cellular Location
Isoform 1: Nucleus; Cytoplasm
Isoform 3: Perinuclear region
PTM
Constitutively tyrosine-phosphorylated. Phosphorylated by TEC (By similarity). Phosphorylated by LYN (By similarity). Phosphorylated on tyrosine residues by the insulin receptor kinase. Results in the negative regulation of the insulin signaling pathway. Phosphorylated on tyrosine residues by SRMS.
View more

Anti-DOK1 antibodies

+ Filters
Loading...

Mouse Anti-dok1 Recombinant Antibody (P0282) (CBMAB-P0282-YC)

Go to compareCompare
Target: DOK1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: P0282
Application*: WB, IP, IF, P
Datasheet SDS

Rabbit Anti-DOK1 Recombinant Antibody (EG986) (V2LY-0425-LY784)

Go to compareCompare
Target: DOK1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG986
Application*: IF, WB
Datasheet SDS

Rabbit Anti-DOK1 Recombinant Antibody (EG985) (V2LY-0425-LY783)

Go to compareCompare
Target: DOK1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG985
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry