FBXL20
Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM
Full Name
F-box and leucine-rich repeat protein 20
Research Area
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission (By similarity).
Biological Process
Behavioral fear response Source: Ensembl
Regulation of protein catabolic process at presynapse, modulating synaptic transmission Source: Ensembl
Regulation of synaptic vesicle exocytosis Source: Ensembl
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: GO_Central
Regulation of protein catabolic process at presynapse, modulating synaptic transmission Source: Ensembl
Regulation of synaptic vesicle exocytosis Source: Ensembl
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: GO_Central
Cellular Location
Cytoplasm
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Anti-FBXL20 antibodies
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Target: FBXL20
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2G1
Application*: WB, E
Target: FBXL20
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1727
Application*: WB, IP, IF, E
Target: FBXL20
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0382
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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