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FLOT2

Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]
Full Name
Flotillin 2
Function
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Biological Process
Anterograde dendritic transport Source: Ensembl
Cell adhesion Source: ProtInc
Epidermis development Source: ProtInc
Membrane raft assembly Source: UniProtKB
Negative regulation of amyloid precursor protein catabolic process Source: UniProtKB
Negative regulation of gene expression Source: UniProtKB
Positive regulation of establishment of T cell polarity Source: UniProtKB
Positive regulation of NF-kappaB transcription factor activity Source: ARUK-UCL
Protein localization to plasma membrane Source: UniProtKB
Protein localization to plasma membrane raft Source: UniProtKB
Protein stabilization Source: UniProtKB
Regulation of myoblast differentiation Source: UniProtKB
Regulation of postsynaptic membrane neurotransmitter receptor levels Source: Ensembl
Cellular Location
Cell membrane; Endosome; Caveola; Membrane. Membrane-associated protein of caveolae.
PTM
ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells.
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Anti-FLOT2 antibodies

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Mouse Anti-FLOT2 Recombinant Antibody (EG1210) (CBMAB-EN1462-LY)

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Target: FLOT2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: EG1210
Application*: WB
Datasheet SDS

Mouse Anti-FLOT2 Recombinant Antibody (3G6) (CBMAB-A3039-LY)

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Target: FLOT2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3G6
Application*: WB, E
Datasheet SDS

Mouse Anti-FLOT2 Recombinant Antibody (CBXF-1976) (CBMAB-F1109-CQ)

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Target: FLOT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Chicken, Dog, Mouse, Rat
Clone: CBXF-1976
Application*: WB, IF, IP
Datasheet SDS

Rabbit Anti-FLOT2 Recombinant Antibody (CBXF-1117) (CBMAB-F0924-CQ)

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Target: FLOT2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1117
Application*: WB, IP
Datasheet SDS

Mouse Anti-FLOT2 Recombinant Antibody (CBXF-0748) (CBMAB-F0436-CQ)

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Target: FLOT2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0748
Application*: IP, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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