FLT3LG

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
Full Name
Fms Related Tyrosine Kinase 3 Ligand
Function
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Biological Process
Embryonic hemopoiesis Source: DFLAT
Positive regulation of cell population proliferation Source: UniProtKB
Signal transduction Source: ProtInc
Cellular Location
Isoform 1: Cell membrane
Isoform 2: Secreted
Topology
Extracellular: 27-184
Helical: 185-205
Cytoplasmic: 206-235
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Anti-FLT3LG antibodies

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Target: FLT3LG
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1215
Application*: WB: 1:500~1:1000 ELISA: 1:20000
Target: FLT3LG
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP773
Application*: ICC, IHC, IP, WB
Target: FLT3LG
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3089
Application*: E, WB
Target: FLT3LG
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: CBXF-1041
Application*: WB, P, F, IF
Target: FLT3LG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8D10
Application*: IF, WB
Target: FLT3LG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2246
Application*: E, N, WB
Target: FLT3LG
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0759
Application*: E, IC, WB
Target: FLT3LG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3325
Application*: WB, N
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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