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Mouse Anti-FLT3LG Recombinant Antibody (CBXF-0759) (CBMAB-F0439-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0759
Antibody Isotype
IgG
Application
ELISA, ICC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fms Related Tyrosine Kinase 3 Ligand
Introduction
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).
Entrez Gene ID
2323
UniProt ID
P49771
Alternative Names
Fms Related Tyrosine Kinase 3 Ligand; Fms-Related Tyrosine Kinase 3 Ligand; Flt3 Ligand; FLT3L; SL Cytokine; FLG3L; FL;
Function
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Biological Process
Embryonic hemopoiesis Source: DFLAT
Positive regulation of cell population proliferation Source: UniProtKB
Signal transduction Source: ProtInc
Cellular Location
Isoform 1: Cell membrane
Isoform 2: Secreted
Topology
Extracellular: 27-184
Helical: 185-205
Cytoplasmic: 206-235
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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