GPR107

Full Name

G Protein-Coupled Receptor 107

Function

Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (PubMed:22933024).

Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).

(Microbial infection) Required for intoxication by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT. May contribute to the retrograde transport of bacterial toxins, including cholera toxin, from the trans-Golgi network to the endoplasmic reticulum.

Biological Process

Clathrin-dependent endocytosis Source: GO_Central

Cellular Location

Trans-Golgi network membrane; Cell membrane

Topology

Extracellular: 40-263
Helical: 264-284
Cytoplasmic: 285-293
Helical: 294-314
Extracellular: 315-337
Helical: 338-358
Cytoplasmic: 359-368
Helical: 369-389
Extracellular: 390-402
Helical: 403-423
Cytoplasmic: 424-498
Helical: 499-519
Extracellular: 520-524
Helical: 525-544
Cytoplasmic: 545-600

PTM

Cleaved by FURIN to yield two fragments of 17 and 35 kDa that remain associated via a disulfide bond.

Anti-GPR107 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Rabbit Anti-GPR107 Recombinant Antibody (EG1358) (CBMAB-EN1637-LY)

Datasheet

SDS

Target: GPR107

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1358

Application*: WB: 1:500~1:1000 ELISA: 1:1000

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)