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GPR173

This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues.
Full Name
G protein-coupled receptor 173
Function
Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity).

It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity).

In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth (PubMed:30933929).
Biological Process
Signal transduction Source: ProtInc
Cellular Location
Cell membrane
Topology
Extracellular: 1-26
Helical: 27-47
Cytoplasmic: 48-59
Helical: 60-80
Extracellular: 81-97
Helical: 98-118
Cytoplasmic: 119-139
Helical: 140-160
Extracellular: 161-188
Helical: 189-209
Cytoplasmic: 210-287
Helical: 288-308
Extracellular: 309-322
Helical: 323-343
Cytoplasmic: 344-373
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Anti-GPR173 antibodies

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Rabbit Anti-GPR173 Recombinant Antibody (EG1392) (CBMAB-EN1671-LY)

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Target: GPR173
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1392
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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