GPR84

GPR84 was activated by MCFAs with the hydroxyl group at the 2- or 3- position more effectively than non-hydroxylated MCFAs.
Full Name
G protein-coupled receptor 84
Function
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
Biological Process
Neuropeptide signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-26
Helical: 27-47
Cytoplasmic: 48-57
Helical: 58-78
Extracellular: 79-94
Helical: 95-115
Cytoplasmic: 116-144
Helical: 145-165
Extracellular: 166-180
Helical: 181-201
Cytoplasmic: 202-320
Helical: 321-341
Extracellular: 342-352
Helical: 353-373
Cytoplasmic: 374-396
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Anti-GPR84 antibodies

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Target: GPR84
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1650
Application*: E, WB
Target: GPR84
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1648
Application*: E, WB
Target: GPR84
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D9
Application*: E, WB, IP
Target: GPR84
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-204
Application*: WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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