ITGB1BP2

This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains.
Full Name
integrin beta 1 binding protein (melusin) 2
Function
May play a role during maturation and/or organization of muscles cells.
Biological Process
Muscle organ developmentManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Z disc
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Anti-ITGB1BP2 antibodies

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Mouse Anti-ITGB1BP2 Recombinant Antibody (3G9) (CBMAB-A4585-LY)

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Target: ITGB1BP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3G9
Application*: WB, E
Datasheet SDS

Mouse Anti-ITGB1BP2 (AA 61-258) Recombinant Antibody (CBFYM-1161) (CBMAB-M1318-FY)

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Target: ITGB1BP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Human, Mouse
Clone: CBFYM-1161
Application*: WB, IF
Datasheet SDS

Mouse Anti-ITGB1BP2 (AA 2-347) Recombinant Antibody (CBFYM-1160) (CBMAB-M1317-FY)

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Target: ITGB1BP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-1160
Application*: WB, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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