Sign in or Register

JTB

JTB is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein kinase binding.
Full Name
jumping translocation breakpoint
Function
Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity).
Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity).
Biological Process
Apoptotic processIEA:UniProtKB-KW
Mitotic cell cycleManual Assertion Based On ExperimentIMP:UniProtKB
Mitotic cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein kinase activityManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Membrane; Mitochondrion; Cytoplasm; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
Topology
Extracellular: 31-105
Helical: 106-126
Cytoplasmic: 127-146
View more

Anti-JTB antibodies

+ Filters
Loading...

Rabbit Anti-JTB Recombinant Antibody (EG1723) (CBMAB-EN2061-LY)

Go to compareCompare
Target: JTB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1723
Application*: WB: 1:500~1:1000 ELISA: 1:1000
Datasheet SDS

Mouse Anti-JTB Recombinant Antibody (CBFYJ-014) (CBMAB-0026-FY)

Go to compareCompare
Target: JTB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYJ-014
Application*: WB
Datasheet SDS

Mouse Anti-JTB Recombinant Antibody (CBFYJ-011) (CBMAB-0023-FY)

Go to compareCompare
Target: JTB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYJ-011
Application*: E, WB
Datasheet SDS

Mouse Anti-JTB Recombinant Antibody (4E7) (CBMAB-0215-WJ)

Go to compareCompare
Target: JTB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4E7
Application*: E, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry