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KHK

This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Full Name
Ketohexokinase
Function
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Biological Process
Fructose metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Regulation of glycogen metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Response to fructoseManual Assertion Based On ExperimentIBA:GO_Central
Response to glucoseManual Assertion Based On ExperimentIBA:GO_Central
Response to insulinManual Assertion Based On ExperimentIBA:GO_Central
Response to sucroseManual Assertion Based On ExperimentIBA:GO_Central
Response to zinc ionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm; Cytosol; Extracellular exosome
Involvement in disease
Fructosuria (FRUCT):
Benign defect of intermediary metabolism.

Anti-KHK antibodies

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Rabbit Anti-KHK Recombinant Antibody (CBLY1-075) (CBMAB-K0804-LY)

Datasheet SDS
Target: KHK
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLY1-075
Application*: WB, IP, P, IC/IF

Mouse Anti-KHK Recombinant Antibody (S1) (CBMAB-K0815-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: S1
Application*: E, IF, WB

Mouse Anti-KHK Recombinant Antibody (4H3) (CBMAB-K0814-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4H3
Application*: F, IC/IF, WB

Mouse Anti-KHK Recombinant Antibody (4E9) (CBMAB-K0813-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E9
Application*: F, IC/IF, IH, P, WB

Mouse Anti-KHK Recombinant Antibody (3D1) (CBMAB-K0811-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3D1
Application*: F, IF, IH, WB

Mouse Anti-KHK Recombinant Antibody (3C4) (CBMAB-K0810-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3C4
Application*: F, IH

Mouse Anti-KHK Recombinant Antibody (2C3) (CBMAB-K0809-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C3
Application*: F, IF, WB

Mouse Anti-KHK Recombinant Antibody (2B1) (CBMAB-K0808-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2B1
Application*: E, WB

Mouse Anti-KHK Recombinant Antibody (1H6-2B6) (CBMAB-K0807-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1H6-2B6
Application*: E, WB

Mouse Anti-KHK Recombinant Antibody (1F1) (CBMAB-K0806-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F1
Application*: F, IF, WB

Mouse Anti-KHK Recombinant Antibody (1D8) (CBMAB-K0805-LY)

Datasheet SDS
Target: KHK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D8
Application*: F, IF, P, WB

KHK Matched Antibody Pair (660) (APMAB-660LY)

Datasheet SDS
Target: KHK
Specificity: Human

KHK Matched Antibody Pair (659) (APMAB-659LY)

Datasheet SDS
Target: KHK
Specificity: Human

KHK Matched Antibody Pair (658) (APMAB-658LY)

Datasheet SDS
Target: KHK
Specificity: Human
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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