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LMO1

LMO1 enocdes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted. [provided by RefSeq]

Full Name

LIM domain only 1 (rhombotin 1)

Function

May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.

Biological Process

Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of T cell homeostatic proliferationIEA:Ensembl

Cellular Location

Nucleus

Involvement in disease

A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD.

Anti-LMO1 antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-LMO1 Recombinant Antibody (4C7) (CBMAB-A5014-LY)

SDS

Target: LMO1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4C7

Application*: WB, E

Mouse Anti-LMO1 Recombinant Antibody (CBYCL-391) (CBMAB-L0292-YC)

SDS

Target: LMO1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYCL-391

Application*: IF, E, WB

Mouse Anti-LMO1 Recombinant Antibody (CBYCL-390) (CBMAB-L0291-YC)

SDS

Target: LMO1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYCL-390

Application*: E, IF, WB

Mouse Anti-LMO1 Recombinant Antibody (CBYJL-1867) (CBMAB-L1852-YJ)

SDS

Target: LMO1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJL-1867

Application*: WB, DB

Mouse Anti-LMO1 Recombinant Antibody (790C2a) (CBMAB-L1850-YJ)

SDS

Target: LMO1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 790C2a

Application*: DB, IC

Mouse Anti-LMO1 Recombinant Antibody (CBYJL-1865) (CBMAB-L1849-YJ)

SDS

Target: LMO1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJL-1865

Application*: E, IF, WB

Mouse Anti-LMO1 Recombinant Antibody (CBYJL-1864) (CBMAB-L1848-YJ)

SDS

Target: LMO1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJL-1864

Application*: E, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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