LMO1

LMO1 enocdes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted. [provided by RefSeq]
Full Name
LIM domain only 1 (rhombotin 1)
Function
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.
Biological Process
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of T cell homeostatic proliferationIEA:Ensembl
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD.
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Anti-LMO1 antibodies

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Mouse Anti-LMO1 Recombinant Antibody (4C7) (CBMAB-A5014-LY)

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Target: LMO1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4C7
Application*: WB, E
Datasheet SDS

Mouse Anti-LMO1 Recombinant Antibody (CBYCL-391) (CBMAB-L0292-YC)

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Target: LMO1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYCL-391
Application*: IF, E, WB
Datasheet SDS

Mouse Anti-LMO1 Recombinant Antibody (CBYCL-390) (CBMAB-L0291-YC)

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Target: LMO1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYCL-390
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-LMO1 Recombinant Antibody (CBYJL-1867) (CBMAB-L1852-YJ)

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Target: LMO1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1867
Application*: WB, DB
Datasheet SDS

Mouse Anti-LMO1 Recombinant Antibody (790C2a) (CBMAB-L1850-YJ)

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Target: LMO1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 790C2a
Application*: DB, IC
Datasheet SDS

Mouse Anti-LMO1 Recombinant Antibody (CBYJL-1865) (CBMAB-L1849-YJ)

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Target: LMO1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1865
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-LMO1 Recombinant Antibody (CBYJL-1864) (CBMAB-L1848-YJ)

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Target: LMO1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1864
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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