MTX1

MTX1 (Metaxin 1) is a Protein Coding gene. Diseases associated with MTX1 include Gaucher's Disease. Among its related pathways are Metabolism of proteins and Mitochondrial protein import. An important paralog of this gene is MTX3.
Full Name
METAXIN 1
Function
Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).
Biological Process
Inner mitochondrial membrane organization Source: UniProtKB
Lactation Source: Ensembl
Mitochondrion organization Source: GO_Central
Protein insertion into mitochondrial outer membrane Source: ComplexPortal
Cellular Location
Mitochondrion
Mitochondrion outer membrane
Other locations
Membrane
Topology
Helical: 421-441
PTM
Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
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Anti-MTX1 antibodies

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Mouse Anti-MTX1 Recombinant Antibody (CBFYM-2778) (CBMAB-M2971-FY)

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Target: MTX1
Host: Mouse
Specificity: Human
Clone: CBFYM-2778
Application*: WB, IP, IF, E
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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