NAALADL1

NAALADase-like activity unknown. Has no NAAG hydrolyzing activity. Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC (By similarity).

Full Name

N-Acetylated Alpha-Linked Acidic Dipeptidase Like 1

Function

Aminopeptidase with broad substrate specificity. Has lower activity with substrates that have Asp or Glu in the P2' position, or Pro in the P3' position. Lacks activity with substrates that have both Pro in the P3' position and Asp or Glu in the P2' position (PubMed:25752612).

Lacks carboxypeptidase activity. Lacks dipeptidyl-peptidase IV type activity (PubMed:25752612).

Biological Process

Peptide catabolic process Source: UniProtKB

Cellular Location

Plasma membrane
Apical cell membrane
Note: Ileal brush border membrane.

Topology

Cytoplasmic: 1-6
Helical: 7-28
Extracellular: 29-740

PTM

N-glycosylated.

Anti-NAALADL1 antibodies

Mouse Anti-NAALADL1 Recombinant Antibody (3C5G10E8) (CBMAB-N1023-WJ)

Datasheet

SDS

Target: NAALADL1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 3C5G10E8

Application*: E

Rabbit Anti-NAALADL1 Recombinant Antibody (CBWJN-1153) (CBMAB-N1022-WJ)

Datasheet

SDS

Target: NAALADL1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBWJN-1153

Application*: WB, E

Rabbit Anti-NAALADL1 Recombinant Antibody (CBWJN-1151) (CBMAB-N1020-WJ)

Datasheet

SDS

Target: NAALADL1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBWJN-1151

Application*: P

Rabbit Anti-NAALADL1 Recombinant Antibody (CBWJN-1150) (CBMAB-N1019-WJ)

Datasheet

SDS

Target: NAALADL1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBWJN-1150

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)