PDF

Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides.

Full Name

PDF

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

Biological Process

Co-translational protein modificationManual Assertion Based On ExperimentIBA:GO_Central
N-terminal protein amino acid modificationManual Assertion Based On ExperimentIDA:HGNC-UCL
Peptidyl-methionine modificationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:HGNC-UCL
TranslationIEA:UniProtKB-KW

Cellular Location

Mitochondrion

Anti-PDF antibodies

Mouse Anti-PDF Recombinant Antibody (CBYC-P254) (CBMAB-P1237-YC)

Datasheet

SDS

Target: PDF

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYC-P254

Application*: WB, IC, P, C, E

Mouse Anti-PDF Recombinant Antibody (CBYC-P253) (CBMAB-P1236-YC)

Datasheet

SDS

Target: PDF

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBYC-P253

Application*: WB, IC, P, C, E

Mouse Anti-PDF Recombinant Antibody (3F3) (CBMAB-P1235-YC)

Datasheet

SDS

Target: PDF

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 3F3

Application*: WB, F, IC, IF

Mouse Anti-PDF Recombinant Antibody (3C12) (CBMAB-P1234-YC)

Datasheet

SDS

Target: PDF

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3C12

Application*: WB, IF, F

Mouse Anti-PDF Recombinant Antibody (CBMAB-0653-LY)

Datasheet

SDS

Target: PDF

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Fruit fly, Cabbage root fly, Cockroach

Application*: IF, IH

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)