PDF

Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides.
Full Name
PDF
Function
Removes the formyl group from the N-terminal Met of newly synthesized proteins.
Biological Process
Co-translational protein modificationManual Assertion Based On ExperimentIBA:GO_Central
N-terminal protein amino acid modificationManual Assertion Based On ExperimentIDA:HGNC-UCL
Peptidyl-methionine modificationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:HGNC-UCL
TranslationIEA:UniProtKB-KW
Cellular Location
Mitochondrion
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Anti-PDF antibodies

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Target: PDF
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYC-P254
Application*: WB, IC, P, C, E
Target: PDF
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYC-P253
Application*: WB, IC, P, C, E
Target: PDF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3F3
Application*: WB, F, IC, IF
Target: PDF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3C12
Application*: WB, IF, F
Target: PDF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Fruit fly, Cabbage root fly, Cockroach
Application*: IF, IH
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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