SCAMP1

This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.

Full Name

Secretory Carrier Membrane Protein 1

Function

Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.

Biological Process

Biological Process endocytosisIEA:Ensembl
Biological Process establishment of localization in cellIEA:Ensembl
Biological Process exocytosisIEA:Ensembl
Biological Process post-Golgi vesicle-mediated transportManual Assertion Based On ExperimentTAS:ProtInc
Biological Process protein transportManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Golgi apparatus, trans-Golgi network membrane
Recycling endosome membrane

Topology

Cytoplasmic: 2-155
Helical: 156-176
Lumenal: 177-181
Helical: 182-202
Cytoplasmic: 203-218
Helical: 219-239
Lumenal: 240-261
Helical: 262-282
Cytoplasmic: 283-338