Tex101

Tex101 plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct probably through molecule adhesion ADAM3. It may function in signal transduction and promote protein tyrosine phosphorylation.

Full Name

Testis Expressed gene 101

Function

Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity).
May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity).

Biological Process

Biological Process binding of sperm to zona pellucidaSource:UniProtKB
Biological Process fertilizationSource:UniProtKB
Biological Process flagellated sperm motilitySource:UniProtKB
Biological Process regulation of flagellated sperm motilitySource:UniProtKB

PTM

N-glycosylated; by high mannose and/or biantennary complex and/or certain types of hybrid oligosaccharides; possesses different oligosaccharides chains according to its subcellular localization in the testis.
Sheds from membrane raft by ACE and released from the cell surface of epididymal sperm while it passes through the caput epididymis leading to disappearance of TEX101 on spermatozoa; is essential to produce fertile spermatozoa.