TRIM44

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]
Full Name
TRIM44 Tripartite Motif Containing 44
Function
May play a role in the process of differentiation and maturation of neuronal cells (By similarity).
May regulate the activity of TRIM17. Is a negative regulator of PAX6 expression (PubMed:26394807).
Biological Process
Biological Process negative regulation of protein K48-linked ubiquitination Source:BHF-UCL1 Publication
Biological Process positive regulation of cytokine-mediated signaling pathway Source:BHF-UCL1 Publication
Biological Process positive regulation of defense response to virus by host Source:BHF-UCL1 Publication
Biological Process positive regulation of DNA-templated transcription Source:BHF-UCL1 Publication
Biological Process positive regulation of NIK/NF-kappaB signaling Source:BHF-UCL1 Publication
Biological Process protein stabilization Source:BHF-UCL1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process regulation of gene expression Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Involvement in disease
Aniridia 3 (AN3):
A form of aniridia, a congenital, bilateral, panocular disorder characterized by complete absence of the iris or extreme iris hypoplasia. Aniridia is not just an isolated defect in iris development but it is associated with macular and optic nerve hypoplasia, cataract, corneal changes, nystagmus. Visual acuity is generally low but is unrelated to the degree of iris hypoplasia. Glaucoma is a secondary problem causing additional visual loss over time.
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Anti-TRIM44 antibodies

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Target: TRIM44
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF454
Application*: ELISA, WB, IF
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4787
Application*: WB, IF
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4786
Application*: WB
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4785
Application*: WB, IH
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-4784
Application*: WB
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4783
Application*: WB, F
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4782
Application*: WB
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4781
Application*: WB, IH, IF
Target: TRIM44
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4780
Application*: E, IF, WB
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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