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Mouse Anti-TRIM44 Recombinant Antibody (CBYJT-4781) (CBMAB-T4322-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TRIM44 (Tripartite Motif Containing 44). The antibody can be used for immunoassay techniques, such as WB, IHC, IF.
See all TRIM44 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4781
Antibody Isotype
IgG1
Application
WB, IHC, IF

Basic Information

Immunogen
Full length human recombinant protein of human TRIM44 (NP_060053) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TRIM44 Tripartite Motif Containing 44
Introduction
TRIM44 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
Entrez Gene ID
54765
UniProt ID
Q96DX7
Alternative Names
Tripartite Motif Containing 44; DIPB; Tripartite Motif-Containing Protein 44; Tripartite Motif-Containing 44; Protein DIPB; HSA249128; AN3; MC7
Function
May play a role in the process of differentiation and maturation of neuronal cells (By similarity).
May regulate the activity of TRIM17. Is a negative regulator of PAX6 expression (PubMed:26394807).
Biological Process
Biological Process negative regulation of protein K48-linked ubiquitination Source:BHF-UCL1 Publication
Biological Process positive regulation of cytokine-mediated signaling pathway Source:BHF-UCL1 Publication
Biological Process positive regulation of defense response to virus by host Source:BHF-UCL1 Publication
Biological Process positive regulation of DNA-templated transcription Source:BHF-UCL1 Publication
Biological Process positive regulation of NIK/NF-kappaB signaling Source:BHF-UCL1 Publication
Biological Process protein stabilization Source:BHF-UCL1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process regulation of gene expression Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Involvement in disease
Aniridia 3 (AN3):
A form of aniridia, a congenital, bilateral, panocular disorder characterized by complete absence of the iris or extreme iris hypoplasia. Aniridia is not just an isolated defect in iris development but it is associated with macular and optic nerve hypoplasia, cataract, corneal changes, nystagmus. Visual acuity is generally low but is unrelated to the degree of iris hypoplasia. Glaucoma is a secondary problem causing additional visual loss over time.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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