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Mouse Anti-F3 Recombinant Antibody (CBYJT-1272) (CBMAB-T0287-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to F3 (Coagulation Factor III, Tissue Factor). The antibody can be used for immunoassay techniques, such as WB, ICC, IHC-P, ELISA.
See all F3 antibodies

Summary

Host Animal
Mouse
Specificity
Rat
Clone
CBYJT-1272
Antibody Isotype
IgG
Application
WB, ICC, IHC-P, ELISA

Basic Information

Immunogen
The antibody is a mouse monoclonal antibody raised against TF. It has beenselected for its ability to recognize TF in immunohistochemical staining andwestern blotting
Specificity
Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Coagulation Factor III, Tissue Factor
Introduction
F3 is an initiation factor for blood coagulation and plays a critical role in hepatic ischemic reperfusion injury.
Entrez Gene ID
25584
UniProt ID
Q66HI4
Alternative Names
tissue factor; TF; coagulation factor 3; coagulation factor III (thromboplastin, tissue factor)
Research Area
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Biological Process
Activation of blood coagulation via clotting cascade Source: BHF-UCL
Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: BHF-UCL
Activation of plasma proteins involved in acute inflammatory response Source: BHF-UCL
Blood coagulation Source: BHF-UCL
Cytokine-mediated signaling pathway Source: GO_Central
Positive regulation of angiogenesis Source: BHF-UCL
Positive regulation of cell migration Source: BHF-UCL
Positive regulation of endothelial cell proliferation Source: BHF-UCL
Positive regulation of gene expression Source: ARUK-UCL
Positive regulation of interleukin-8 production Source: ARUK-UCL
Positive regulation of platelet-derived growth factor receptor signaling pathway Source: BHF-UCL
Positive regulation of positive chemotaxis Source: BHF-UCL
Positive regulation of protein kinase B signaling Source: BHF-UCL
Protein processing Source: BHF-UCL
Cellular Location
Isoform 1: Membrane
Isoform 2: Secreted
Topology
Extracellular: 33-251
Helical: 252-274
Cytoplasmic: 275-295
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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