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Rabbit Anti-FABP6 Recombinant Antibody (CBXF-0249) (CBMAB-F1188-CQ)

This product is a rabbit antibody that recognizes FABP6. The antibody CBXF-0249 can be used for immunoassay techniques such as: IF.
See all FABP6 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXF-0249
Antibody Isotype
IgG
Application
IF

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 5% trehalose
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
fatty acid binding protein 6, ileal
Introduction
This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene.
Entrez Gene ID
2172
UniProt ID
P51161
Alternative Names
Fatty Acid Binding Protein 6; Fatty Acid Binding Protein 6, Ileal; Ileal Bile Acid Binding Protein; Illeal Lipid-Binding Protein; Ileal Lipid-Binding Protein; Intestinal 15 KDa Protein; Gastrotropin; I-BABP; I-15P;
Research Area
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity).

In vitro binds to bile acids in the order: deoxycholic acid> cholic acid> chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated> glycine-conjugated> unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity).
Isoform 2:
Essential for the survival of colon cancer cells to bile acid-induced apoptosis.
Biological Process
Lipid metabolic process Source: ProtInc
Lipid transport Source: UniProtKB-KW
Negative regulation of cell population proliferation Source: ProtInc
Cellular Location
Isoform 1: Cytoplasm; Membrane
Isoform 2: Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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