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Rabbit Anti-FCRL2 Recombinant Antibody (CBXF-1137) (CBMAB-F0840-CQ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXF-1137
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fc Receptor Like 2
Introduction
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Entrez Gene ID
79368
UniProt ID
Q96LA5
Alternative Names
Fc Receptor Like 2; Immunoglobulin Receptor Translocation-Associated Protein 4; SH2 Domain-Containing Phosphatase Anchor Protein 1; Fc Receptor Homolog 2; IFGP Family Protein 4; SPAP1; FCRH2; IFGP4; IRTA4; SH2 Domain Containing Phosphatase Anchor Protein 1; Immune Receptor Translocation-Associated Protein 4;
Research Area
May have an regulatory role in normal and neoplastic B cell development.
Biological Process
Cell-cell signaling Source: UniProtKB
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 20-401
Helical: 402-422
Cytoplasmic: 423-508
PTM
Isoform 2 is N- and O-glycosylated, and phosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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