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Mouse Anti-FGF6 (AA 53-208) Recombinant Antibody (CBXF-2624) (CBMAB-F3051-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-2624
Antibody Isotype
IgG1
Application
Neut, ELISA(Cap)

Basic Information

Immunogen
E. coli-derived recombinant human FGF-6, Ala53-Ile208, Accession # P10767
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with trehalose
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 53-208

Target

Full Name
Fibroblast Growth Factor 6
Introduction
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
Entrez Gene ID
2251
UniProt ID
P10767
Alternative Names
Fibroblast Growth Factor 6; Heparin Secretory-Transforming Protein 2; Heparin-Binding Growth Factor 6; HBGF-6; HSTF-2; FGF-6; HST-2; HST2; HSTF2;
Research Area
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.
Biological Process
Angiogenesis Source: UniProtKB-KW
Animal organ morphogenesis Source: GO_Central
Cartilage condensation Source: Ensembl
Cell differentiation Source: GO_Central
Fibroblast growth factor receptor signaling pathway Source: MGI
Myoblast differentiation Source: Ensembl
Positive regulation of cell division Source: UniProtKB-KW
Positive regulation of cell population proliferation Source: MGI
Positive regulation of gene expression Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Regulation of cell migration Source: GO_Central
Cellular Location
Extracellular space
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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