Sign in or Register   Sign in or Register
  |  

Mouse Anti-FKBP3 Recombinant Antibody (CBXF-3048) (CBMAB-F3750-CQ)

This product is a mouse antibody that recognizes FKBP3. The antibody CBXF-3048 can be used for immunoassay techniques such as: WB.
See all FKBP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBXF-3048
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Partial sequence of recombinant full-length protein to human FK506 Binding Protein 3
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FK506 Binding Protein 3
Introduction
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Entrez Gene ID
Human2287
Mouse30795
Rat299104
UniProt ID
HumanQ00688
MouseQ62446
RatG3V6L9
Alternative Names
FK506 Binding Protein 3; Rapamycin-Selective 25 KDa Immunophilin; FK506 Binding Protein 3, 25kDa; 25 KDa FK506-Binding Protein; Immunophilin FKBP25; PPIase FKBP3; 25 KDa FKBP; Rotamase; FKBP-25; FKBP-3;
Function
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
Cellular Location
Nucleus
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-FKBP3 Recombinant Antibody (CBXF-3048)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare