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Rabbit Anti-FOSL1 (Phosphorylated S265) Recombinant Antibody (D22B1) (PTM-CBMAB-0580LY)

This antibody is a recombiant antibody against FRA1. The antibody can be used for immunoassay techniques, such as WB, ChIP.
See all FOSL1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat, Monkey, Cattle
Clone
D22B1
Antibody Isotype
IgG
Application
WB, ChIP

Basic Information

Specificity
Human, Mouse, Rat, Monkey, Cattle
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
FOS like 1, AP-1 transcription factor subunit
Entrez Gene ID
Human8061
Mouse14283
Rat25445
Monkey106993191
Cattle531389
UniProt ID
HumanP15407
MouseP48755
RatP10158
MonkeyA0A2K5VU76
CattleE1BNB5
Biological Process
Cellular defense response Source: ProtInc
Cellular response to extracellular stimulus Source: Ensembl
Chemotaxis Source: ProtInc
Female pregnancy Source: Ensembl
In utero embryonic development Source: Ensembl
Learning Source: Ensembl
Negative regulation of cell population proliferation Source: Ensembl
Placenta blood vessel development Source: Ensembl
Positive regulation of apoptotic process Source: Ensembl
Positive regulation of cell cycle Source: Ensembl
Positive regulation of cell population proliferation Source: ProtInc
Positive regulation of DNA-binding transcription factor activity Source: Ensembl
Positive regulation of DNA-templated transcription, initiation Source: CACAO
Positive regulation of pri-miRNA transcription by RNA polymerase II Source: BHF-UCL
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to cAMP Source: Ensembl
Response to corticosterone Source: Ensembl
Response to cytokine Source: Ensembl
Response to drug Source: Ensembl
Response to gravity Source: Ensembl
Response to hydrogen peroxide Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to progesterone Source: Ensembl
Response to virus Source: ProtInc
Vitellogenesis Source: Ensembl
Cellular Location
Nucleus

Sobolev, V. V., Khashukoeva, A. Z., Evina, O. E., Geppe, N. A., Chebysheva, S. N., Korsunskaya, I. M., ... & Mezentsev, A. (2022). Role of the transcription factor FOSL1 in organ development and tumorigenesis. International journal of molecular sciences, 23(3), 1521.

Shetty, A., Tripathi, S. K., Junttila, S., Buchacher, T., Biradar, R., Bhosale, S. D., ... & Lahesmaa, R. (2022). A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation. Nucleic acids research, 50(9), 4938-4958.

Pecce, V., Verrienti, A., Fiscon, G., Sponziello, M., Conte, F., Abballe, L., ... & Paci, P. (2021). The role of FOSL1 in stem-like cell reprogramming processes. Scientific reports, 11(1), 1-11.

Vallejo, A., Erice, O., Entrialgo-Cadierno, R., Feliu, I., Guruceaga, E., Perugorria, M. J., ... & Vicent, S. (2021). FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted. Journal of hepatology, 75(2), 363-376.

Zhang, M., Hoyle, R. G., Ma, Z., Sun, B., Cai, W., Cai, H., ... & Li, J. (2021). FOSL1 promotes metastasis of head and neck squamous cell carcinoma through super-enhancer-driven transcription program. Molecular Therapy, 29(8), 2583-2600.

Dai, C., Rennhack, J. P., Arnoff, T. E., Thaker, M., Younger, S. T., Doench, J. G., ... & Hahn, W. C. (2021). SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization. Cell reports, 36(4), 109443.

Nitkin, C. R., Xia, S., Menden, H., Yu, W., Xiong, M., Heruth, D. P., ... & Sampath, V. (2020). FOSL1 is a novel mediator of endotoxin/lipopolysaccharide-induced pulmonary angiogenic signaling. Scientific Reports, 10(1), 13143.

Chen, S., Youhong, T., Tan, Y., He, Y., Ban, Y., Cai, J., ... & Xiang, B. (2020). EGFR-PKM2 signaling promotes the metastatic potential of nasopharyngeal carcinoma through induction of FOSL1 and ANTXR2. Carcinogenesis, 41(6), 723-733.

He, S. W., Xu, C., Li, Y. Q., Li, Y. Q., Zhao, Y., Zhang, P. P., ... & Liu, N. (2020). AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma. Oncogene, 39(34), 5616-5632.

Chen, X., Zhao, M., Huang, J., Li, Y., Wang, S., Harrington, C. A., ... & Dai, M. S. (2018). MicroRNA‐130a suppresses breast cancer cell migration and invasion by targeting FOSL1 and upregulating ZO‐1. Journal of cellular biochemistry, 119(6), 4945-4956.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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