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  • Mouse Anti-GPR157 Recombinant Antibody (CBLG1-3202)

Mouse Anti-GPR157 Recombinant Antibody (CBLG1-3202) (CBMAB-G4634-LY)

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Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBLG1-3202
Application
WB
Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
G protein-coupled receptor 157
Entrez Gene ID
Human80045
Mouse269604
Rat313725
UniProt ID
HumanQ5UAW9
MouseQ8C206
RatQ5FVG1
Function
Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.
Biological Process
Cell surface receptor signaling pathway Source: InterPro
Circadian behavior Source: Ensembl
G protein-coupled receptor signaling pathway Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling Pathway Source: UniProtKB
Radial glial cell differentiation Source: UniProtKB
Cellular Location
Cilium membrane. Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid.
Topology
Extracellular: 1-15
Helical: 16-36
Cytoplasmic: 37-48
Helical: 49-69
Extracellular: 70-87
Helical: 88-108
Cytoplasmic: 109-119
Helical: 120-140
Extracellular: 141-166
Helical: 167-187
Cytoplasmic: 188-226
Helical: 227-247
Extracellular: 248-258
Helical: 259-279
Cytoplasmic: 280-335

Guo, H., Du, X., Zhang, Y., Wu, J., Wang, C., Li, M., ... & Yan, J. (2019). Specific miRNA-G protein-coupled receptor networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish. Stem Cells, 37(9), 1189-1199.

Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A., Peters, J. A., Veale, E. L., ... & CGTP Collaborators. (2019). The Concise Guide to PHARMACOLOGY 2019/20: G protein-coupled receptors. British Journal of Pharmacology, 176(Suppl 1).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-GPR157 Recombinant Antibody (EG1387) (CAT#: CBMAB-EN1666-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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