Rabbit Anti-GPR157 Recombinant Antibody (EG1387) (CBMAB-EN1666-LY)

Name: Rabbit Anti-GPR157 Recombinant Antibody (EG1387)
SKU: CBMAB-EN1666-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1387

Application

WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human GPR157.

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

G protein-coupled receptor 157

Entrez Gene ID

80045

UniProt ID

Q5UAW9

Function

Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.

Biological Process

Cell surface receptor signaling pathway Source: InterPro
Circadian behavior Source: Ensembl
G protein-coupled receptor signaling pathway Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling Pathway Source: UniProtKB
Radial glial cell differentiation Source: UniProtKB

Cellular Location

Cilium membrane. Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid.

Topology

Extracellular: 1-15
Helical: 16-36
Cytoplasmic: 37-48
Helical: 49-69
Extracellular: 70-87
Helical: 88-108
Cytoplasmic: 109-119
Helical: 120-140
Extracellular: 141-166
Helical: 167-187
Cytoplasmic: 188-226
Helical: 227-247
Extracellular: 248-258
Helical: 259-279
Cytoplasmic: 280-335

Guo, H., Du, X., Zhang, Y., Wu, J., Wang, C., Li, M., ... & Yan, J. (2019). Specific miRNA-G protein-coupled receptor networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish. Stem Cells, 37(9), 1189-1199.

Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A., Peters, J. A., Veale, E. L., ... & CGTP Collaborators. (2019). The Concise Guide to PHARMACOLOGY 2019/20: G protein-coupled receptors. British Journal of Pharmacology, 176(Suppl 1).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-GPR157 Recombinant Antibody (CBLG1-3202) (CAT#: CBMAB-G4634-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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