GPR157

Full Name
G protein-coupled receptor 157
Function
Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.
Biological Process
Cell surface receptor signaling pathway Source: InterPro
Circadian behavior Source: Ensembl
G protein-coupled receptor signaling pathway Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling Pathway Source: UniProtKB
Radial glial cell differentiation Source: UniProtKB
Cellular Location
Cilium membrane. Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid.
Topology
Extracellular: 1-15
Helical: 16-36
Cytoplasmic: 37-48
Helical: 49-69
Extracellular: 70-87
Helical: 88-108
Cytoplasmic: 109-119
Helical: 120-140
Extracellular: 141-166
Helical: 167-187
Cytoplasmic: 188-226
Helical: 227-247
Extracellular: 248-258
Helical: 259-279
Cytoplasmic: 280-335
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Anti-GPR157 antibodies

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Target: GPR157
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1387
Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000
Target: GPR157
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLG1-3202
Application*: WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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