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Mouse Anti-GTF2A1 Antibody (1F2) (CBMAB-0421-YC)

Provided herein are mouse monoclonal antibodies against Human GTF2A1. The antibody clone 1F2 can be used for immunoassay techniques, such as IP and MA.
See all GTF2A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F2
Antibody Isotype
IgG2b
Application
IP, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
GTF2A1
Introduction
TFIIA is one of general initiation factors, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits. TFIIA involves in accurate transcription initiation on TATA-containing class II genes.
Entrez Gene ID
2957
UniProt ID
P52655
Alternative Names
TFIIA
Function
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
Biological Process
Positive regulation of transcription by RNA polymerase II Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Transcription by RNA polymerase II Source: ARUK-UCL
Transcription initiation from RNA polymerase II promoter Source: InterPro
Cellular Location
Nucleus
PTM
The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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