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GTF2A1

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.

Full Name

GTF2A1

Function

TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

Biological Process

Positive regulation of transcription by RNA polymerase II Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Transcription by RNA polymerase II Source: ARUK-UCL
Transcription initiation from RNA polymerase II promoter Source: InterPro

Cellular Location

Nucleus

PTM

The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation.

Anti-GTF2A1 antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-GTF2A1 Recombinant Antibody (CBLG1-2087) (CBMAB-G5639-LY)

SDS

Target: GTF2A1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBLG1-2087

Application*: WB

Mouse Anti-GTF2A1 Recombinant Antibody (CBLG1-2086) (CBMAB-G5638-LY)

SDS

Target: GTF2A1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBLG1-2086

Application*: SE, E, WB

Mouse Anti-GTF2A1 Recombinant Antibody (5F12) (CBMAB-G5636-LY)

SDS

Target: GTF2A1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 5F12

Application*: E, WB

Mouse Anti-GTF2A1 Recombinant Antibody (2H5) (CBMAB-G5635-LY)

SDS

Target: GTF2A1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2H5

Application*: E, WB

Mouse Anti-GTF2A1 Recombinant Antibody (708C4a) (CBMAB-G0919-LY)

SDS

Target: GTF2A1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 708C4a

Application*: DB

Mouse Anti-GTF2A1 Antibody (1F2) (CBMAB-0421-YC)

SDS

Target: GTF2A1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1F2

Application*: IP, M

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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