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Mouse Anti-GTF2A1 Recombinant Antibody (CBLG1-2087) (CBMAB-G5639-LY)

This product is antibody recognizes GTF2A1. The antibody CBLG1-2087 immunoassay techniques such as: WB.
See all GTF2A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-2087
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Recombinant human General Transcription Factor IIA, Polypeptide 1, 19/37kD
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GTF2A1
Introduction
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]
Entrez Gene ID
2957
UniProt ID
P52655
Alternative Names
General Transcription Factor IIA Subunit 1; Transcription Initiation Factor TFIIA 42 KDa Subunit; General Transcription Factor IIA; 1; 19/37kDa; Glucose Regulated Protein; 58kD Pseudogene; General Transcription Factor IIA 1; TFIIA Alpha/Beta Subunits; TFIIA-42;
Function
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
Biological Process
Positive regulation of transcription by RNA polymerase II Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Transcription by RNA polymerase II Source: ARUK-UCL
Transcription initiation from RNA polymerase II promoter Source: InterPro
Cellular Location
Nucleus
PTM
The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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