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EPOR Matched Antibody Pair (387) (APMAB-387LY)

This antibody pair set can be used for detecting and quantifying protein level of human EPOR.
See all EPOR antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-EPOR monoclonal antibody, 100 ug
Detection Antibody
Anti-EPOR Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Alternative Names
Erythropoietin Receptor; EPO-R;
Entrez Gene ID
2057
UniProt ID
P19235

Mochida, Y., Hara, A., Oka, M., Maesato, K., Ishioka, K., Moriya, H., ... & Wada, T. (2022). Association between Anti-Erythropoietin Receptor Antibodies and Cardiac Function in Patients on Hemodialysis: A Multicenter Cross-Sectional Study. Biomedicines, 10(9), 2092.

Papic, M., Zivanovic, S., Vucicevic, T., Papic, M. V., Zdravkovic, D., Milivojevic, N., ... & Popovic, M. (2022). Pulpal expression of erythropoietin and erythropoietin receptor after direct pulp capping in rat. European Journal of Oral Sciences, e12888.

Ramshekar, A., Bretz, C. A., Kunz, E., Cung, T., Richards, B. T., Stoddard, G. J., ... & Hartnett, M. E. (2022). Role of Erythropoietin Receptor Signaling in Macrophages or Choroidal Endothelial Cells in Choroidal Neovascularization. Biomedicines, 10(7), 1655.

Nijholt, K. T., Meems, L. M., Ruifrok, W., Maass, A. H., Yurista, S. R., Pavez-Giani, M. G., ... & Westenbrink, B. D. (2021). The erythropoietin receptor expressed in skeletal muscle is essential for mitochondrial biogenesis and physiological exercise. Pflügers Archiv-European Journal of Physiology, 473(8), 1301-1313.

Oshima, M., Hara, A., Toyama, T., Jun, M., Pollock, C., Jardine, M., ... & Wada, T. (2021). Comparison of circulating biomarkers in predicting diabetic kidney disease progression with autoantibodies to erythropoietin receptor. Kidney international reports, 6(2), 284-295.

Vukelic, J., Dobrila-Dintinjana, R., Marijic, B., Marzic, D., Braut, T., & Velepic, M. (2021). New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue. Medicine, 100(3).

Wu, B. W., Liu, Y., Wu, M. S., Meng, Y. H., Lu, M., Guo, J. D., & Zhou, Y. H. (2020). Downregulation of microRNA‐135b promotes atherosclerotic plaque stabilization in atherosclerotic mice by upregulating erythropoietin receptor. IUBMB life, 72(2), 198-213.

Bretz, C. A., Simmons, A. B., Kunz, E., Ramshekar, A., Kennedy, C., Cardenas, I., & Hartnett, M. E. (2020). Erythropoietin receptor signaling supports retinal function after vascular injury. The American journal of pathology, 190(3), 630-641.

Shi, M., Flores, B., Li, P., Gillings, N., McMillan, K. L., Ye, J., ... & Hu, M. C. (2018). Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a “U-shaped” relationship. American Journal of Physiology-Renal Physiology, 314(4), F501-F516.

Ostrowski, D., & Heinrich, R. (2018). Alternative erythropoietin receptors in the nervous system. Journal of Clinical Medicine, 7(2), 24.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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