ACP1
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]
Full Name
Acid Phosphatase 1
Function
Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
Cellular Location
Cytoplasm
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Anti-ACP1 antibodies
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Target: ACP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: V2-610932
Application*: WB, E
Target: ACP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-179368
Application*: E, C, IC, IF, WB
Target: ACP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: V2-179366
Application*: E, WB
Target: ACP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-179365
Application*: E, WB
Target: ACP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: V2-179364
Application*: WB
Target: ACP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: V2-58750
Application*: WB, E, IC, IF
Target: ACP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-55264
Application*: WB, IC, P, C, E
Target: ACP1
Expressed Host: E. coli
Sequence: Amino Acid: 1-158
Tag: GST Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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