AMT

AMT is one of four critical components of the glycine cleavage system. Mutations in this gene have been associated with glycine encephalopathy.

Full Name

Aminomethyltransferase

Function

The glycine cleavage system catalyzes the degradation of glycine.

Biological Process

Glycine catabolic process Source: Reactome
Glycine decarboxylation via glycine cleavage system Source: UniProtKB

Cellular Location

Mitochondrion

Involvement in disease

Non-ketotic hyperglycinemia (NKH): Autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.

Anti-AMT antibodies

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Mouse Anti-AMT Recombinant Antibody (6F4) (CBMAB-A2592-YC)

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Target: AMT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: 6F4

Application*: WB, IH

Datasheet SDS

Mouse Anti-AMT Recombinant Antibody (4C9) (CBMAB-A2590-YC)

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Target: AMT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: 4C9

Application*: WB

Datasheet SDS

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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