ATP23
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
Full Name
ATP23 Metallopeptidase And ATP Synthase Assembly Factor Homolog
Biological Process
Double-strand break repair via nonhomologous end joining Source: UniProtKB
Mitochondrial protein processing Source: GO_Central
Mitochondrial proton-transporting ATP synthase complex assembly Source: GO_Central
Mitochondrial protein processing Source: GO_Central
Mitochondrial proton-transporting ATP synthase complex assembly Source: GO_Central
Cellular Location
Cytosol; Extrinsic component of mitochondrial inner membrane; DNA-dependent protein kinase-DNA ligase 4 complex; Plasma membrane; Cell junction; Intracellular membrane-bounded organelle
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Anti-ATP23 antibodies
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Target: ATP23
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G6
Application*: E
Target: ATP23
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3C5
Application*: WB
Target: ATP23
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F3
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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