BDH1

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

3-Hydroxybutyrate Dehydrogenase 1

Ketone body biosynthetic process Source: Reactome
Ketone body catabolic process Source: Reactome

Mitochondrion inner membrane; Mitochondrion matrix