BLVRB
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM
Full Name
biliverdin reductase B (flavin reductase (NADPH))
Function
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe3+ iron to Fe2+ in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Biological Process
Heme catabolic process Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-BLVRB antibodies
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Target: BLVRB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-1663
Application*: WB, E, IP
Target: BLVRB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBLG1-340
Application*: WB, IP, IF, E
Target: BLVRB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2F4
Application*: E, WB
Target: BLVRB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1655
Application*: WB
Target: BLVRB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-0629
Application*: E
Target: BLVRB
Expressed Host: E. coli
Sequence: Amino Acid: 2-206
Tag: His Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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