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CALN1

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Full Name

calneuron 1

Function

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.

Cellular Location

Trans-Golgi network membrane; Cell membrane; Perinuclear region

Topology

Cytoplasmic: 1-234 aa
Helical: 235-255 aa
Extracellular: 256-261 aa

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Anti-CALN1 antibodies

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Mouse Anti-CALN1 Recombinant Antibody (2G2) (CBMAB-C5161-LY)

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Target: CALN1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G2

Application*: E, WB

Mouse Anti-CALN1 Recombinant Antibody (2G5) (CBMAB-C5188-LY)

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Target: CALN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2G5

Application*: E, WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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