CALN1

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Full Name

calneuron 1

Function

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.

Cellular Location

Trans-Golgi network membrane; Cell membrane; Perinuclear region

Topology

Cytoplasmic: 1-234 aa
Helical: 235-255 aa
Extracellular: 256-261 aa

Anti-CALN1 antibodies

Mouse Anti-CALN1 Recombinant Antibody (2G5) (CBMAB-C5188-LY)

Datasheet

SDS

Target: CALN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2G5

Application*: E, WB

Mouse Anti-CALN1 Recombinant Antibody (2G2) (CBMAB-C5161-LY)

Datasheet

SDS

Target: CALN1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G2

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)